Cushing’s disease, also known as hyperadrenocorticism, is a disease caused by the overproduction of cortisol. The average age for a dog to be diagnosed with Cushing’s disease is seven to nine years old. By partnering with your pet’s veterinarian, the disease and its associated clinical signs can be successfully managed. [H2]   Monitor your dog carefully for any of the clinical signs associated with Cushing’s Disease. Symptoms vary depending on the case, but can include:   

Have your dog evaluated by a veterinarian if you notice they are exhibiting these symptoms.  

A full physical examination with complete history gathered will be completed. If clinical signs associated with Cushing’s are present, your veterinarian may recommend complete blood cell count, blood chemistry, and a urinalysis as baseline diagnostics. Depending on blood work results, your veterinarian may recommend specific adrenal gland testing such as a low-dose dexamethasone suppression test, ACTH stimulation test, and urine cortisol: creatine ratio (UCCR). Other testing like an abdominal ultrasound may be recommended to look at the adrenal glands. Based on the results of the testing, therapy may be indicated. Thrive Plus membership can support your pet and your wallet, too.  

There are three types of Cushing’s disease. Each results in excess cortisol levels in the body, but for different reasons:  

1. Pituitary-dependent Cushing’s disease 

Overproduction of cortisol comes from the adrenal gland due to a usually benign tumor in the pituitary gland. 

2. Adrenal-dependent Cushing’s disease

Overproduction of cortisol comes from the adrenal glands due to a tumor. Dogs with adrenal tumors tend to be older. 

3. Iatrogenic Cushing’s disease

Overproduction of cortisol comes as a secondary result of medications such as steroids. 

Most pituitary-dependent Cushing’s disease is treated with oral medications such as Trilostane. If so, your veterinarian will recommend rechecking blood work about every 6 months to make sure the therapy is effective. 

If adrenal-based Cushing’s disease is suspected, which is rare, surgery may be recommended. 

If your dog starts showing a relapse in clinical signs it is important to let your veterinarian know as dose adjustments may be recommended. 

Careful monitoring of your pet is essential to detect disease as early as possible. Cushing’s disease in dogs can be successfully managed and treated by partnering with your veterinarian.   

With our Thrive Plus membership, you can get unlimited FREE exams to check up on your pet’s chronic illness, like Cushing’s disease, as often as needed. And members get 10% off medications, surgeries, and diagnostics like blood work to check that treatment is working successfully.*   

Our shared hope is to see every pet thrive, so book an appointment today if you feel your dog is showing signs of Cushing’s disease or if you would like to explore an individualized treatment plan for your dog who has been diagnosed. 

 

*12–month commitment required. See Thrive Plus Terms and Conditions for additional terms.